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Thursday 29 January 2015

The Benefits Of Using The Liposomal Encapsulation Technology

By Kristen Baird


The use of liposome in clinical medicine first came to trial in the 1960s, and research and clinical trials that have since followed made sure that this amazing technological evolution can now be applied for both clinical therapy and in other aspect of life. However, the liposomal encapsulation technology (LET) is still in its early stages of development, with little information known to the wider public.

Unlike other methods like in the use of needles for injections, swallowing of tablets, capsules or even syrup where the drug or the substance has to directly pass through the body tissues that are not the direct target, leading to possible reactions, loss of concentration or even interfering with the normal body functions, this method of drug administration employs an ingenious solution to drug administration. In fact, clinical trials have proven that it is better way of treating racehorses without the need of needles or syringes.

In this technology, phospholipid membrane (liposome) is used to encase a prescribed amount of pharmaceutical compounds with the aim of preventing their degradation as they pass through the gastrointestinal tract. This option offers an excellent transfer mechanism that is not available with other drug administration methods. The method is now used in other fields other than in clinical therapies. These include supplement manufacturers, topical moisturizers and the beauty product manufacturers among others.

Phospholipid liposome comes in to withstand the impact of anybody radicals, particularly the enzymes, the body moisture, the alkaline fluids, and the salts within the digestive tract. The compounds being introduced in the body are well protected all the way to the time they are delivered to the targeted organs or the tissue. At this point, a chain reaction takes place, allowing the cells to open up their walls, allowing the compound into the intracellular medium to commence the process of treatment.

The effectiveness of this technology relies on the fact that liposomes easily penetrate cell walls and many other infectious biofilms, which allows for a highly effective delivery system against these pathological infections. Research has found that 5 grams of Vitamin C encased in liposomes is as effective as 50 grams of Vitamin C that is delivered intravenously demonstrating how effective this technology is in terms of delivery of compounds to the targeted tissues.

The LET is a clinical therapy that is associated with numerous strengths as compared to most commonly used drug administration methods. The nutrients and active ingredients are transported directly to the point of the target, leaving little or no interference with the normal body functioning such as blood pressure, the balanced body pH, and other normal metabolic functions. This makes a lot of sense for the patient is able to recover with fewer side effects associated with the drug. It also comes with economic sense as it cuts down on the cost of clinical therapy.

The use of phospholipids also comes with numerous benefits to the body. It cuts down on serum lipids, decreases platelet aggregation, bad cholesterol, triglyceride, and increases good cholesterol, and the fluidity of red blood cells gets amplified. In addition to these, it helps boost immunity, improves quality of memory, protects the liver and improves the ability of the body to endure exercise.

LET comes with a number of benefits, but it is still advisable to consider all other therapy alternatives available and come up with the best and most comprehensive method to administer drugs.




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